Opioids - Revision history

Aesetholephews at 20:58, 31 January 2023

2023-01-31T20:58:17Z

Aesetholephews at 20:50, 31 January 2023

2023-01-31T20:50:41Z

Aesetholephews at 19:51, 29 August 2022

2022-08-29T19:51:07Z

Aesetholephews at 13:50, 2 August 2022

2022-08-02T13:50:05Z

Aesetholephews at 17:04, 18 July 2022

2022-07-18T17:04:45Z

Aesetholephews: Created page with "* Don’t combine benzodiazepines and opioids. If you need to reverse, use flumazenil. =Short-Acting= * Oxycodone, Hydromorphone, Morphine =Long-Acting= * Oxycodone ER = OxyC..."

2022-07-18T17:03:46Z

Created page with "* Don’t combine benzodiazepines and opioids. If you need to reverse, use flumazenil. =Short-Acting= * Oxycodone, Hydromorphone, Morphine =Long-Acting= * Oxycodone ER = OxyC..."

New page

* Don’t combine benzodiazepines and opioids. If you need to reverse, use flumazenil.
=Short-Acting=
* Oxycodone, Hydromorphone, Morphine
=Long-Acting=
* Oxycodone ER = OxyContin
* Morphine can cause rash/pruritis
* Fentanyl is really only used intra-op or in palliative care.

@@ Line 4: / Line 4: @@
 ! Opioid !! Dose !! Onset !! Duration !! Elimination !! Unique effects/indications
 |-
-| Fentanyl || 1-20 ug/kg || 4-6 min || 15-30 min || Hepatic/Renal || Example
+| Fentanyl || 1-20 ug/kg || 4-6 min || 30-45 min || Hepatic || Not used as infusion
 |-
-| Sufentanyl || 0.3-1 ug/kg || 2-4 min || 5-15 min || Hepatic/Renal || Example
+| Sufentanyl || 0.3-1 ug/kg || 1-2 min || 20-40 min || Hepatic || ...
 |-
-| Remifentanyl || 0.1-0.3 ug/kg || 1-2 min || 2-5 min || Plasma esterases || Example
+| Remifentanyl || 0.3-1 ug/kg || 1-1.5 min || 5-10 min || Plasma esterases, context sensitive half-life || Profound hypotension/bradycardia, "MAC sparing" reduces need for other anesthetics by 75%
 |-
-| Alfentanyl || 15-50 ug/kg || Example || Example || Hepatic/Renal || Example
+| Alfentanyl || 5-50 ug/kg || 1-2 min || 20 min || Hepatic || ...
 |-
-| Morphine sulfate || 25-75 mg || 10-30 min || 2-5 hrs || Example || Can cause histamine release
+| Morphine sulfate || 25-75 mg || 10-30 min || 2-5 hrs || Hepatic || Can cause histamine release
 |-
-| Meperidine || Example || 10-30 min || 2-5 hrs || Example || Used for post-op shivering
+| Meperidine || Example || 10-30 min || 2-5 hrs || Hepatic || Used for post-op shivering, can't give to patients taking MAOIs
 |}

← Older revision		Revision as of 20:50, 31 January 2023
Line 1:		Line 1:
		+	{\| class="wikitable"
		+	\|+ Commonly Used Opioids
		+	\|-
		+	! Opioid !! Dose !! Onset !! Duration !! Elimination !! Unique effects/indications
		+	\|-
		+	\| Fentanyl \|\| 1-20 ug/kg \|\| 4-6 min \|\| 15-30 min \|\| Hepatic/Renal \|\| Example
		+	\|-
		+	\| Sufentanyl \|\| 0.3-1 ug/kg \|\| 2-4 min \|\| 5-15 min \|\| Hepatic/Renal \|\| Example
		+	\|-
		+	\| Remifentanyl \|\| 0.1-0.3 ug/kg \|\| 1-2 min \|\| 2-5 min \|\| Plasma esterases \|\| Example
		+	\|-
		+	\| Alfentanyl \|\| 15-50 ug/kg \|\| Example \|\| Example \|\| Hepatic/Renal \|\| Example
		+	\|-
		+	\| Morphine sulfate \|\| 25-75 mg \|\| 10-30 min \|\| 2-5 hrs \|\| Example \|\| Can cause histamine release
		+	\|-
		+	\| Meperidine \|\| Example \|\| 10-30 min \|\| 2-5 hrs \|\| Example \|\| Used for post-op shivering
		+	\|}
		+
	* Don’t combine [[benzodiazepines]] and opioids. If you need to reverse, use [[flumazenil]].		* Don’t combine [[benzodiazepines]] and opioids. If you need to reverse, use [[flumazenil]].
	* Central loci of opioid action (descending inhibitory pain pathways)		* Central loci of opioid action (descending inhibitory pain pathways)

@@ Line 1: / Line 1: @@
 * Don’t combine [[benzodiazepines]] and opioids. If you need to reverse, use [[flumazenil]].
 =Short-Acting=
 * Oxycodone, Hydromorphone, Morphine

@@ Line 2: / Line 2: @@
 =Short-Acting=
 * Oxycodone, Hydromorphone, Morphine
 =Long-Acting=
 * Oxycodone ER = OxyContin
-* Morphine can cause rash/pruritis
+* Methadone
 * Fentanyl is really only used intra-op or in palliative care.