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[https://dx.doi.org/10.1097/EJA.0000000000001881 Maesen, EJA 2023] Systematic review showing that periop interventions that reduced post-op pain include APAP, NSAIDs, IV Mg, IV dexmedetomidine, and parasternal block.

[https://dx.doi.org/10.3390/jcm12052060 Pascarella, J of Clin Med 2023] A prospective study showing that US-guided[Preoperative] parasternal block provided an optimal perioperative analgesia with a significant reduction in intraoperative opioid consumption, time to extubation and a better postoperative performance at spirometry when compared to the Control group.

[https://dx.doi.org/10.4103/aer.AER_32_20 Vilvanathan, Anes: Essays and Research 2020] A prospective, randomized, double-blinded interventional study showing that PIB is safe for presternotomy administration and provided significant quality of pain relief postoperatively, as seen after tracheal extubation for a period of 24 h, on rest as well as with deep breathing, coughing, and chest physiotherapy exercises when compared to intravenous morphine alone after sternotomy.

[https://dx.doi.org/10.1111/jocs.16882 King, J of Card Surg 2022] A systematic review and meta-analysis showing that following median sternotomy both postoperative pain (SMD [95% CI] -0.49 [-0.92 to -0.06]) and postoperative morphine equivalent use (SMD [95% CI] -1.68 [-3.11 to -0.25]) were significantly less in the PSB group.

[https://dx.doi.org/10.1053/j.jvca.2022.07.025 Schiavoni, J of CT & Vasc Anes 2022] Parasternal block has been shown to reduce perioperative opioid consumption and provide a more favorable analgesic profile, with reduced postoperative opioid-related side effects. A trend toward reduced intensive care unit stay or duration of mechanical ventilation should be confirmed by adequately powered randomized trials or registry studies.

[https://dx.doi.org/10.23736/S0375-9393.22.16272-3 Li, Minerva Anes 2022] A total of 12 RCTs with 366 patients in PSB group and 364 patients in control group were included in the present meta-analysis. Pooled analysis revealed that intraoperative and postoperative consumption of sufentanil were significantly decreased with the addition of PSB (P<0.05). Numerical rating scale (NRS) scores in PSB group were found to be significantly lower than that of control group at extubation, postoperative 4 h and 8 h (P<0.05) instead of postoperative 24 h or longer. PSB could reduce the incidence of postoperative nausea and vomiting (PONV) (P<0.05). In addition, we demonstrated that PSB was significantly related to decreased mechanical ventilation time, total length of ICU stay and hospital days (P<0.05).

Parasternal Block - Revision history

Aesetholephews: Created page with "[https://dx.doi.org/10.1097/EJA.0000000000001881 Maesen, EJA 2023] Systematic review showing that periop interventions that reduced post-op pain include APAP, NSAIDs, IV Mg, I..."