SCD Fluid Bolus - Revision history

Aesetholephews: /* SCD hemodynamic effects */

2026-11-11T22:29:59Z

SCD hemodynamic effects

2026-11-11T18:25:26Z

SCD hemodynamic effects

2026-11-11T17:22:59Z

SCD hemodynamic effects

2026-11-11T17:10:37Z

SCD hemodynamic effects

2026-11-11T16:59:19Z

Exclusion Criteria

2026-11-11T16:58:49Z

Study Design

2024-11-21T20:39:33Z

Study Design

2024-11-18T23:14:12Z

Exclusion Criteria

2024-11-18T23:13:52Z

Inclusion Criteria

2024-11-18T23:13:43Z

Study Design

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 =SCD hemodynamic effects=
 {| class="wikitable"
 |+ Caption text

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 |Unblinded, RCT, IPC initiation at time of spinal
 |No IPCs
-|Phenylephrine rate and incidence of hypotension were lower in the IPC group, but the total dose was not different (thought it trended to favor IPC).
+|Phenylephrine rate and incidence of hypotension were lower in the IPC group, but the total dose was not different (though it trended to favor IPC).
 |}

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+|
 |Simultaneous 30 mmHg led to the greatest increase in Peak Systolic Velocity (PSV) in the common femoral vein as measured by doppler US, while intermittent led to a slower PSV but longer augmentation, potentially equating to greater total venous return.
 |}

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 |-
 | [https://pubmed.ncbi.nlm.nih.gov/18219162/ Sohn et al Circulation J 2008] || Example || Example || Example || Example
 |}

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 * Cardiogenic pulmonary edema
 * Tricuspid regurgitation
-* Common adverse effects of both compression stockings and IPC include skin pressure injury, pruritus (itching) and discomfort; and both are contraindicated in people with severe peripheral arterial disease (PAD) [16, 17, 18]. [https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD016365/full source]
+* Common adverse effects of both compression stockings and IPC include skin pressure injury, pruritus (itching) and discomfort; and both are contraindicated in people with severe peripheral arterial disease (PAD) [16, 17, 18]. IPC is also contraindicated in people with lower‐limb ischaemia, active skin infection, and active DVT or pulmonary embolism [14, 19]. [https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD016365/full source]
 =SCD hemodynamic effects=

← Older revision		Revision as of 20:39, 21 November 2024
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		+	IDEs can be foregone if any of the exemption criteria at 21 CFR 812.2(c) (Investigational Device Exemptions 2014) are met. [...] A diagnostic device, if the sponsor complies with applicable requirements in 21 CFR 809.10(c) and if the testing: is non-invasive, does not introduce energy into the patients body, has the diagnosis confirmed by a medically accepted alternate method.
		+
	=Study Design=		=Study Design=
	==Inclusion Criteria==		==Inclusion Criteria==

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 ==Exclusion Criteria==
 * LIMITS [https://annalsofintensivecare.springeropen.com/articles/10.1186/s13613-022-01022-8 mnemonic]
-* Low HR/RR ratio
+** Low HR/RR ratio
-* Irregular rhythm
+** Irregular rhythm
-* Mechanical ventilation w/ low VT
+** Mechanical ventilation w/ low VT
-* Increased intra-abdominal pressure (e.g. insufflation)
+** Increased intra-abdominal pressure (e.g. insufflation)
-* Thorax Open
+** Thorax Open
-* Spontaneously breathing
+** Spontaneously breathing
 * Cardiogenic pulmonary edema
 * Tricuspid regurgitation

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 * NSR
 * Positive pressure ventilation
-==Exclusion Criteria (LIMITS [https://annalsofintensivecare.springeropen.com/articles/10.1186/s13613-022-01022-8 mnemonic])==
 * Low HR/RR ratio
 * Irregular rhythm