Difference between revisions of "Low vs. High FiO2"

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(Created page with "* High FiO2 is pro-inflammatory (pro-cancer?), generates ROS, drives resorption atelectasis, worsens HPV, may not prevent SSI. * High FiO2 undeniably buys apnea time * Extubat...")
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Revision as of 20:43, 29 September 2026

  • High FiO2 is pro-inflammatory (pro-cancer?), generates ROS, drives resorption atelectasis, worsens HPV, may not prevent SSI.
  • High FiO2 undeniably buys apnea time
  • Extubation practices vary, but one common practice is to remove PEEP, and turn FiO2 to 100%.
  • This practice is associated with worsened post-extubation atelectasis and end-expiratory lung volumes (EELV) according to a 2026 BJA paper from a team at BIDMC who used EIT to measure atelectasis and lung volumes. Conversely, using an FiO2 of 40% or 70% was shown to decrease atelectasis and increase EELV.