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→Mechanisms of Anesthesia
* ''C. elegans'' don't have any histamine signaling natively. You can make animals that express histamine-gated chloride channels to chemogenetically inactivate channel expressing neurons when histamine is given exogenously. '''Look for a GABA<sub>A</sub>R His-Cl worm line.
* ''C. elegans'' don't have any histamine signaling natively. You can make animals that express histamine-gated chloride channels to chemogenetically inactivate channel expressing neurons when histamine is given exogenously. '''Look for a GABA<sub>A</sub>R His-Cl worm line.
** He is going to send me some links to worm genetic databases, and some protocols for breeding and behavior.
** He is going to send me some links to worm genetic databases, and some protocols for breeding and behavior.
===EEG Approach===
*Emergence from different anesthetics in patients with SEEG implants. Can we correlate this with fMRI and scalp EEG or eCOG?
*Is emergence just induction backwards? If not, what can that tell you about mechanisms?
===Phylogenetic Approach===
===Phylogenetic Approach===