Changes

**'''Is there anything in the literature that can guide a protocol modification?'''

**'''Is there anything in the literature that can guide a protocol modification?'''

**'''Systematic review and meta analysis'''

**'''Systematic review and meta analysis'''

**Can we leverage Ripple hardware/BATMAN (lab-grade, non-FDA approved device) to entrain or modulate alpha band?

**Use Ripple hardware/BATMAN (lab-grade, non-FDA approved device) to do a sweep of different entrainment techniques in sedated ICU patients to find the best settings/timing.

*Can I incorporate pain/withdrawal thresholds since everyone's pain tolerance might be different.

*Can I incorporate pain/withdrawal thresholds since everyone's pain tolerance might be different.

*Make it multi-center

*Make it multi-center