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175 bytes added ,  00:27, 27 April 2023
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=Calculating A-a gradient=
 
=Calculating A-a gradient=
Get an ABG. Then use the A-a gradient equation: PAO2 - PaO2 = ([Patm - PH2O] x FiO2 - [PaCO2/Q]) - PaO2 = ([Patm - 47] x FiO2 - [PaCO2/0.8]) - PaO2 = (150 - [PaCO2/0.8]) - PaO2, when at sea level with a patient breathing room air.
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Get an ABG. Then use the alveolar gas equation:  
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A-a gradient increases with age, use equation: (Age+10)/4.
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*PAO2 - PaO2
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*PAO2 = ([Patm - PH2O] x FiO2 - [PaCO2/Q])
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*PAO2 = ([Patm - 47] x FiO2 - [PaCO2/0.8])
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*PAO2 = (150 - [PaCO2/0.8]) (when at sea level with a patient breathing room air)
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Normal A-a gradient increases with age, use the equation: (Age+10)/4.
    
=Differential=
 
=Differential=
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** Hypoventilation (increased PaCO2)
 
** Hypoventilation (increased PaCO2)
 
** Low SvO2 (low cardiac output, high O2 consumption)
 
** Low SvO2 (low cardiac output, high O2 consumption)
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=Special Situations=
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*CCBs can be a 'gas-fire on atelectasis' due to pulmonary vasodilation and disruption of V/Q matching leading to worsened shunt and hypoxemia

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