Difference between revisions of "Diuretics"
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(Created page with "{| class="wikitable" |+ Diuretics |- ! Class !! Site of action !! Examples !! Na Reabsorption |- | Carbonic anhydrase inhibitors || Proximal convoluted tubule || Acetazolamide...") |
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| Potassium sparing || Collecting duct || Spironolactone, Amiloride || 2-3% | | Potassium sparing || Collecting duct || Spironolactone, Amiloride || 2-3% | ||
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| + | Sequential nephron blockade involves choosing multiple diuretics with different sites of action, avoid blocking all four segments though. | ||
Revision as of 23:07, 29 April 2023
| Class | Site of action | Examples | Na Reabsorption |
|---|---|---|---|
| Carbonic anhydrase inhibitors | Proximal convoluted tubule | Acetazolamide | 69% |
| Loop | Thick ascending limb of loop of Henle | Furosemide, Bumetanide | 20% |
| Thiazide | Distal convoluted tubule | HCTZ, Metolazone, Chlorthalidone | 3-8% |
| Potassium sparing | Collecting duct | Spironolactone, Amiloride | 2-3% |
Sequential nephron blockade involves choosing multiple diuretics with different sites of action, avoid blocking all four segments though.