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Line 12: − =HIT= − *Tx: Discontinuation of heparin and transition to a DOAC if anticoagulation is still required (Warfarin causes transient hyper coagulable state due to '''depletion of protein of C'''). '''Avoidance of heparin for life'''
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=HIT=
*Tx: Discontinuation of heparin and transition to a DOAC if anticoagulation is still required (Warfarin causes transient hyper coagulable state due to '''depletion of protein of C'''). '''Avoidance of heparin for life'''
=Multiple Myeloma=
=Multiple Myeloma=
*H&P: Often presents with CRAB symptoms (Calcium, Renal failure, Anemia, or Bone lesions) or frequent infections. Can be complicated by unstable bradycardia, osteoporosis, ATN (via IG light chain, an endogenous nephrotoxin), nephrotic syndrome secondary to renal (AL) amyloidosis, type II RTA
*H&P: Often presents with CRAB symptoms (Calcium, Renal failure, Anemia, or Bone lesions) or frequent infections. Can be complicated by unstable bradycardia, osteoporosis, ATN (via IG light chain, an endogenous nephrotoxin), nephrotic syndrome secondary to renal (AL) amyloidosis, type II RTA
*Factor V Leiden accounts for about 50% of hereditary thrombophilia.
*Factor V Leiden accounts for about 50% of hereditary thrombophilia.
*Technetium-99 bone scan detects plastic lesions, CT detects lytic lesions.
*Technetium-99 bone scan detects plastic lesions, CT detects lytic lesions.