Changes

===Mechanisms of Anesthesia===

===Mechanisms of Anesthesia===

'''Big picture:''' understand the temporospatial and mechanistic changes in neural activity induced by various anesthetics. Can we recapitulate those with steerable, low latency, closed-loop non-invasive neuromodulation or use this knowledge to drive discovery of novel drugs?

'''Big picture:''' understand the temporospatial and mechanistic changes in neural activity induced by various anesthetics. Can we recapitulate those with steerable, low latency, closed-loop non-invasive neuromodulation or use this knowledge to drive discovery of novel drugs?

*High-throughput screen of anesthetics (and anesthetic reversal agents) in C.elegans. I could work in parallel in a different organism (e.g. yeast, jellyfish, hydra, sea anemones, corral, bacteria, plants, neuronal explants).

*High-throughput screen of anesthetics (and anesthetic reversal agents) in ''C.elegans''. I could work in parallel in a different organism (e.g. yeast, jellyfish, hydra, sea anemones, corral, bacteria, plants, neuronal explants).

*'''Has anyone published behavioral assays for these organisms? Detailed protocols for breeding them? Have they already been anesthetized?'''

*'''Has anyone published behavioral assays for these organisms? Detailed protocols for breeding them? Have they already been anesthetized?'''