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==Exacerbation==
=Grade and Group=
* GOLD grades 1-4 based on FEV1 % of predicted.
* GOLD group based on mMRC, number of exacerbations per year.
=Exacerbation=
* O2 administration improves oxygenation to areas of lung with '''low''' V/Q ratio
* increase in sputum volume, purulence, and dyspnea
* increase in sputum volume, purulence, and dyspnea
* severe: all 3 present
* severe: all 3 present
* mild: 1 of the above, plus another finding such as URI, fever, cough, wheezing
* mild: 1 of the above, plus another finding such as URI, fever, cough, wheezing
* treatment depends on severity.
* treatment depends on severity.
=Treatment=
* O2 goal 88-92%, because they are dependent on hypoxia for respiratory drive, since they are chronically hypercapnic.
* O2 goal 88-92%, because they are dependent on hypoxia for respiratory drive, since they are chronically hypercapnic.