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→Diagnosis
==Diagnosis==
==Diagnosis==
* SIRS, severe sepsis, and septic shock are outdated concepts from the 1990s.
* SIRS, severe sepsis, and septic shock are outdated concepts from the 1990s.
* Most recent guidelines from 2016 Surviving Sepsis
* Most recent definitions are from [[2016 Surviving Sepsis | https://oce.ovid.com/article/00005407-201602230-00023]]
** Life threatening organ dysfunction due to systemic infection
** Life threatening organ dysfunction due to systemic infection
** qSOFA or SOFA score are screening tools for organ dysfunction, NOT for sepsis
** qSOFA (outpatient) or SOFA (ICU) score are screening tools for organ dysfunction, NOT for sepsis
** [[Shock]]: Persistent hypotension, not responsive to fluids, requiring pressors to keep [[MAP]] > 65, and lactate > 2
** [[Shock]]: Persistent hypotension, not responsive to fluids, requiring pressors to keep [[MAP]] > 65, and lactate > 2