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→Diagnosis
* SIRS, severe sepsis, and septic shock are outdated concepts from the 1990s.
* SIRS, severe sepsis, and septic shock are outdated concepts from the 1990s.
* Most recent definitions are from [[https://oce.ovid.com/article/00005407-201602230-00023|2016 Surviving Sepsis]]
* Most recent definitions are from [[https://oce.ovid.com/article/00005407-201602230-00023|2016 Surviving Sepsis]]
** Life threatening organ dysfunction due to systemic infection
** "Life-threatening organ dysfunction caused by a dysregulated host response to infection"
** qSOFA (outpatient) or SOFA (ICU) score are screening tools for organ dysfunction, NOT for sepsis
** qSOFA (outpatient) or SOFA (ICU) score are screening tools for organ dysfunction, NOT for sepsis
** [[Shock]]: Persistent hypotension, not responsive to fluids, requiring pressors to keep [[MAP]] > 65, and lactate > 2
** [[Shock]]: Persistent hypotension, not responsive to fluids, requiring pressors to keep [[MAP]] > 65, and lactate > 2