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Line 168: − + − + − **Can I incorporate pain/withdrawal thresholds since everyone's pain tolerance might be different.+ − **Make it multi-center − **'''Is alpha dropout selective for certain types of pain?''' − **Power analysis based on pilot study − + + + + + +
→Alpha entrainment analgesia study
==CLAN==
==CLAN==
===Alpha entrainment analgesia study===
===Alpha entrainment analgesia study===
*How to leverage Ripple hardware/BATMAN (lab-grade, non-FDA approved device) to entrain or modulate alpha band?
*Successfully entrain alpha.
**Successfully entrain alpha. What were we doing wrong? '''Is there anything in the literature that can guide a protocol modification?'''
**What were we doing wrong?
**'''Is there anything in the literature that can guide a protocol modification?'''
**'''Systematic review and meta analysis'''
**'''Systematic review and meta analysis'''
**Stimulation of inhibitory neurons in the ACC expressing channelrhodopsin-2 resulted in a reduction of reflexive acute pain responses in mice.
**Can we leverage Ripple hardware/BATMAN (lab-grade, non-FDA approved device) to entrain or modulate alpha band?
*Can I incorporate pain/withdrawal thresholds since everyone's pain tolerance might be different.
*Make it multi-center
*'''Is alpha dropout selective for certain types of pain?'''
*Power analysis based on pilot study
*Stimulation of inhibitory neurons in the ACC expressing channelrhodopsin-2 resulted in a reduction of reflexive acute pain responses in mice.
====EEG nociceptive signatures====
====EEG nociceptive signatures====
*See Naloxone below for a start.
*See Naloxone below for a start.